Selected Publications

  1. Stark JM, Liu J, Tibbitt CA, Christian M, Ma J, Wintersand A, Dunst J, Kreslavsky T, Murrell B, Adner M, Grönlund H, Gafvelin G, Coquet JM. Recombinant multimeric dog allergen prevents airway hyperresponsiveness in a model of asthma marked by vigorous TH 2 and TH 17 cell responses. Allergy. 2022 Oct;77(10):2987-3001. doi: 10.1111/all.15399. Epub 2022 Jun 20. PubMed PMID: 35657107; PubMed Central PMCID: PMC9796107.
  2. Jankovic D, Ciucci T, Coffman RL, Coquet JM, Le Gros G, Mosmann TR, Sher A, Ronchese F. Comment on: Repositioning TH cell polarization from single cytokines to complex help. Nat Immunol. 2022 Apr;23(4):501-502. doi: 10.1038/s41590-022-01144-y. PubMed PMID: 35190720.
  3. Classon CH, Li M, Clavero AL, Ma J, Feng X, Tibbitt CA, Stark JM, Cardoso R, Ringqvist E, Boon L, Villablanca EJ, Rothfuchs AG, Eidsmo L, Coquet JM, Nylén S. Intestinal helminth infection transforms the CD4+ T cell composition of the skin. Mucosal Immunol. 2022 Feb;15(2):257-267. doi: 10.1038/s41385-021-00473-9. Epub 2021 Dec 20. PubMed PMID: 34931000; PubMed Central PMCID: PMC8866128.
  4. Ma J, Tibbitt CA, Georén SK, Christian M, Murrell B, Cardell LO, Bachert C, Coquet JM. Single-cell analysis pinpoints distinct populations of cytotoxic CD4+ T cells and an IL-10+CD109+ TH2 cell population in nasal polyps. Science Immunol. 2021 Aug 13;6(62). doi: 10.1126/sciimmunol.abg6356. PubMed PMID: 34389612.
  5. Sheward DJ, Mandolesi M, Urgard E, Kim C, Hanke L, Perez Vidakovics L, Pankow A, Smith NL, Castro Dopico X, McInerney GM, Coquet JM, Karlsson Hedestam GB, Murrell B. Beta RBD boost broadens antibody-mediated protection against SARS-CoV-2 variants in animal models. Cell Rep Med. 2021 Nov 16;2(11):100450. doi: 10.1016/j.xcrm.2021.100450. Epub 2021 Oct 23. PubMed PMID: 34723224; PubMed Central PMCID: PMC8536561.
  6. Stark JM, Coquet JM, Tibbitt CA. The Role of PPAR-γ in Allergic Disease. Curr Allergy Asthma Rep. 2021 Oct 25;21(11):45. doi: 10.1007/s11882-021-01022-x. Review. PubMed PMID: 34697644; PubMed Central PMCID: PMC8545719.
  7. Rohrbeck L, Adori M, Wang S, He C, Tibbitt CA, Chernyshev M, Sirel M, Ribacke U, Murrell B, Bohlooly-Y M, Karlsson MC, Karlsson Hedestam GB, Coquet JM. GPR43 regulates marginal zone B-cell responses to foreign and endogenous antigens. Immunol Cell Biol. 2021 Feb;99(2):234-243. doi: 10.1111/imcb.12399. Epub 2020 Sep 28. PubMed PMID: 32888232
  8. Coquet JM. A singular role for interleukin-9 in the development of asthma. Science Immunol. 2020 Jun 12;5(48). doi: 10.1126/sciimmunol.abc4021. Review. PubMed PMID: 32532833.
  9. Batyrova B, Luwaert F, Maravelia P, Miyabayashi Y, Vashist N, Stark JM, Soori SY, Tibbitt CA, Riese P, Coquet JM, Chambers BJ. PD-1 expression affects cytokine production by ILC2 and is influenced by peroxisome proliferator-activated receptor-γ. Immun Inflamm Dis. 2020 Mar;8(1):8-23. doi: 10.1002/iid3.279. Epub 2019 Nov 19. PubMed PMID: 31742928; PubMed Central PMCID: PMC7016838.
  10. Stark JM, Tibbitt CA, Coquet JM. The Metabolic Requirements of Th2 Cell Differentiation. Front Immunol. 2019;10:2318. doi: 10.3389/fimmu.2019.02318. eCollection 2019. Review.
  11. Tibbitt CA, Stark JM, Martens L, Ma J, Mold JE, Deswarte K, Oliynyk G, Feng X, Lambrecht BN, De Bleser P, Nylén S, Hammad H, Arsenian Henriksson M, Saeys Y, Coquet JM. Single-Cell RNA Sequencing of the T Helper Cell Response to House Dust Mites Defines a Distinct Gene Expression Signature in Airway Th2 Cells. Immunity. 2019 Jul 16;51(1):169-184.e5. doi: 10.1016/j.immuni.2019.05.014. Epub 2019 Jun 20. PubMed PMID: 31231035.Tibbitt et al., full
  12. Seitz C, Liu S, Klocke K, Joly AL, Czarnewski PV, Tibbitt C, Parigi SM, Westerberg LS, Coquet JM, Villablanca EJ, Wing K, Andersson J. Multi-faceted inhibition of dendritic cell function by CD4+Foxp3+regulatory T cells.  J Autoimmunity. 2019 Jan 4. pii: S0896-8411(18)30438-4. doi: 10.1016/j.jaut.2018.12.002. PubMed PMID: 30616979 Link
  13. Feng X, Classon C, Yang G, Lei L, Chan S, Rothfuchs A, Coquet JM and Nylén S. Atrophy of skin-draining lymph nodes predisposes for impaired immune responses to secondary infection in mice with chronic nematode infection. Plos Pathogens. 2018. May 17; 14(5):e1007008. PMID: 29772005 Link
  14. Centa M, Prokopec KE, Garimella M, Habir K, Hofste L, Stark J, Dahdah A, Tibbitt C, Polyzos KA, Gisterå A, Johansson DK, Maeda NN, Hansson GK, Ketelhuth DFJ, Coquet JM, Binder CJ, Karlsson MCI and Malin S. Acute loss of Apolipoprotein E triggers an autoimmune response that accelerates atherosclerosis. Arteriosclerosis, Thrombosis and Vascular Biology. 2018. Jun 7. DOI: 10.1161/ATVBAHA.118.310802. PMID: 29880490 Link
  15. Coquet JM. Factoring in CD4 T cells during treatment of HIV. Immunol Cell Biol. May 16. DOI: 10.1038/icb.2017.37 Link
  16. Chen T, Tibbitt CA Feng X, Stark JM, Rohrbeck L, Rausch L, Sedimbi S, Karlsson M, Lambrecht BN, Karlsson Hedestam G, Hendriks RW, Chambers B, Nylén S and Coquet JM. PPAR-gamma promotes type 2 immune responses in allergy and nematode infection. Science Immunology. 2017 10March;2(9):DOI:10.1126/sciimmunol-aal5196 Link
  17. Carow B, Gao Y, Coquet JM, Reilly M and Rottenberg ME. Lck-driven Cre expression alters thymic T cell development, and frequencies and activation of peripheral T cell subsets. J Immunol. 2016 Aug 8, PMID: 27503210 Link
  18. Drennan MB, Govindarajan S, Verheugen E, Coquet JM, McGuire C, Staal J, Beyaert R, van Loo G, Lambrecht BN, Elewaut D. NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20. J Exp Med. 2016 Aug 22;213(10) Link
  19. Tibbitt C and Coquet JM. House dust mite extract and cytokine instillation of mouse airways and subsequent cellular analysis. Bio-protocol. 2016;6(14):e1875 Link
  20. Coquet JM, Schuijs M, Smyth MJ, Deswarte K, Beyaert R, Braun H, Boon L, Karlsson Hedestam GB, Nutt SL, Hammad H, Lambrecht BN. Interleukin-21-producing CD4(+) T cells promote type 2 immunity to house dust mites. Immunity. 2015;43:318-30. Link
  21. Coquet JM, Rausch L and Borst J. The importance of co-stimulation in the orchestration of T helper cell differentiation. Immunol Cell Biol. 2015;93:780-8. Review Link